As far as the game goes, I can see it going either way. I think there's a real chance that Bakhtiari, Bulaga, Perry, and Daniels are all out again. That's a lot of top players to be without. And then you have the issue with the decimated OT depth. The Bears are playing well at the moment, however it's hard to say how the Packers will defend a running team.
Working in the Packers' favor is the home field advantage on a short week. The road teams tend to struggle more often in these TNF games. I also think it's a positive that edge rushing hasn't been the Bears' bread and butter to this point in the season (though that may change in a hurry against the Packers' tackles). Their three main edge players, Will Young, Leonard Floyd, and Pernell McPhee, have combined for 3 sacks so far this season. Akiem Hicks has been their best player in the front seven thus far, and it will be much easier for this depleted line to deal with an interior threat than an exterior one.
I think the Packers need to incorporate a lot of the screen game, and get some of these young backs into the mix to see if they can make anything pop in the running game. slow down the rush that way, and then see if you can make something work on the outside. Whatever they do will be tough and subject to a lot of busted plays just given what they're working with at tackle.
If they can scratch, claw, and win ugly, that would be huge. A loss doesn't sink them. But it's a huge bonus to pick up W's when the team is so banged up. Either way, the 10 day lay-off will be big.